2. Rachel McAdams (Regina George)
Rachel has been very successful since she starred as the Queen B of the “The Plastics.” McAdams went on to star alongside Ryan Gosling in the romantic blockbuster, The Notebook that same year. She’s also been in Wedding Crashers, The Vow, The Time Traveler’s Wife, Red Eye, State of Play, Sherlock Holmes, Midnight in Paris and A Most Wanted Man, just to name a few.
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