11. Christina Applegate
Christina Applegate starting acting in 1981 at the age of ten, and got her big break on Married With Children as Kelly Bundy. We’ve since seen her on the big screen in films like The Sweetest Thing, Hall Pass and the Anchorman movies. On the small screen, she’s helmed shows like Jesse, Samantha Who? and Up All Night. As a breast cancer survivor, she is an outspoken advocate for the disease.
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