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10 Actors Whose Careers Died After Leaving Their Hit Show

2. Katherine Heigl

Katherine Heigl had it made as Izzie Stevens on the hit show Grey’s Anatomy, but she felt her star was shining a bit too brightly for the show. It all started in 2008 when she withdrew herself from Emmy nominations, citing her lackluster character as the reason she was undeserving of the recognition. After six seasons, she left the show and jumped feet first into starring in a few box office hits, such as Knocked Up, and 27 Dresses, but her career came to a screeching halt soon thereafter. She has been in a string of bad movies, and had to resort to kitty litter and Nyquil commercials to make a living.

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