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10 Actors Whose Careers Died After Leaving Their Hit Show

1. Charlie Sheen

Charlie Sheen was on top of the world as Charlie Harper on Two and a Half Men, but his hard-partying off the set caught up to him, and he was booted from the show after making derogatory comments about the program’s Jewish creator. Following his departure, he was in and out of jail and rehab for substance abuse issues and domestic violence charges. These days, his health is his biggest priority, after coming clean about his HIV-positive status.

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